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Master of Science in Nursing (MSN) students are tasked with taking on leadership roles in healthcare. This paper delves into advanced nursing practice, with a focus on leadership, policy development, and the role of advanced practice nurses (APNs). It highlights the application of clinical expertise, management strategies, and the influence of health policy in shaping healthcare systems. The discussion provides insights into how MSN graduates can act as change agents in fostering quality care and innovative approaches within their organizations.